Zebrago Industrial Co., Limited

Eucommia ulmoides Extract

    roduct Name: Eucommia Ulmoides Extract

    Product Specification : Chlorogenic acid 25%,30%,50%,90%,98%

    Product Name: Eucommia Leaf Extract
    Latin Name: Eucommia Ulmoids Oliv.

    Appearance: Brown powder 
    Part of the Plant Used:Leaf

    Extract Method: Grain Alcohol/Water
 Eucommia (Eucommia Ulmoides), commonly called the hardy rubber tree or the gutta-percha tree. The Chinese name for eucommia bark is Du Zhong. Eucommia is mainly grown in temperate regions of Asia mostly in China such as Guizhou, Sichuan, Hunan. The medicinal use of Eucommia ulmoides dates back to ancient Traditional Medicinal Chinese including the texts of Yellow Emperor’s Internal Classic (Huangdi Neijing) (475-221BC). It has been used classically as a combination with other medicinal herbs or as a single agent to treat lower back pain and knees and strengthening the tendons and bones. In addition, it has also been used for prevention of miscarriage. In modern medicine, majority of the preliminary data lend support to its use in osteoporosis, arthritis, hypertension with purported actions such as anti-oxidant and anti-inflammatory properties.


roduct Name:

Eucommia Ulmoides Extract

Test Method:


Latin Name:

 Eucommia Ulmoids Oliv.

Country of Origin:


Part Used:


Type of extraction:         



1. It is associated with the liver and kidneys, and is considered the primary herb used to increase yang functions in the body. 
2. Eucommia bark strengthens the bones and muscles, heals injured and weakened tissues, and can treat lower back and leg pain, stiffness and arthritis. 
3. In addition to its healing effects, eucommia has the ability to lower blood pressure; most Chinese formulas used to lower blood pressure contain at least some amount of eucommia.
4. It is also given to pregnant women to calm the fetus and prevent miscarriage.


1About pharmacodynamics study

  It is investigated that chlorogenicacid has a poor absorption when taken by mouth with a little part of which absorbed in small intestine while most of it will be absorbed in the terms of benzoic acid acid exists in the form of metabolites in the blood plasma. Protein binding: It is proved by test in vitro that chlogogenic acid can bind with HAS in different concentration. There is only one combine site in low concentration. It appears to be several sites in high concentration in the region of HAS and IIA. Excretion: chlogogenic acid and its metabolites in blood plasma mainly discharged through kidney but discharged along with urine when it taken by mouth.and benzene propanoic acid and cinnamic acid. Therefore chlorogenic

1) The protection to cardiovascular

A large number of experiments have show that Chlorogenic acid, as a kind of free radical scavenger and antioxidant, has a good protection to cardiovascular. Chang Cuiqing proved that chlorogenic acid has a preparatory prevention to the damage of endothelial cells induced by ox-LDL. Chlopcikova discovered that chlorogenic can protect Myocardium cell from being damaged by oxidant of Doxombiein,DOx and has a prominent inhibition of peroxidization of mitochondria envelope lipid induced by iron reserves dependence DOX. It goes to show chlorogenic acid can protect vascular endothelium cell by removing radical intermediate and antioxidant lipids and has a further prevention to arteriosclerosishypertension and thrombosis.

2) Anti-mutagens and anti-cance 

 The experiment of animals shows that chlorogenic acid can prevent and inhibit colon cancer and stomach cancer. Jiang discovered chlorogenic acid brought bigger DNA fragments produced by tumor cells and its agglutination. Aryl hydrocarbon hydroxylase is an important Metabolizing Enzyme of polynuclear aromatic and its activeness would improve the mutagens of anti- polynuclear aromatic of tissue cells. Research in vitro discovered that chlorogenic acid can improve the activeness of Aryl hydrocarbon hydroxylase. It also can inhibit the formation of 8-OHdG and the grow of Escherichia foetidaStaphylococcus aureusblack hay bacillus and legionella.

3) Reduce blood fat

Veins have given chlorogenic the power of reducing cholesterol and triglycerides in the blood of rats. When adding chlorogenic acid to the food of rats, it discovered that the cholesterol in rats lungs and livers has also reduced.

4) Anti-leukemia

Chiang found that chlorogenic acid had light activeness of anti-leukemia by the experiment in vitro. J. Bandyopadhyay has proved that chlorogenic acid can inhibit Ber-Abl and c-Abl and induce the dead of the original lymphocytosis in the body of leukemia patients.

5) Adjust the immune function

 The research in vitro has showed chlorogenic acid can obviously strengthen T cells caused by influenza as well as induce humans lymphocytes and albumen cells to produce 7-IFN and α-IFN. It can improve the lgG1 and Ll4 level of rats. In a recent research, it is discovered that chlorogenic acid has the ability to activate nerve cardiac troponin to strengthen the function of macrophages.

6) Lower glucose

It is proved by the research of Andrade-Cetto and Wiedenfeld H that

Chlorogenic acid has potential function in lowering glucose in animals body. The function may have relationships with the inhibiting of glucose-6- and the absorption of glucose.





Brown  powder

chlorogenic acid V by HPLC


chlorogenic acid by UV




Sieve analysis

100% pass 80 mesh

Loss on Drying




Heavy Metal








Total Plate Count


Yeast & Mold








Conform with specification


Store in sealed containers at cool & dry place.


Protect from light, moisture and pest infestation.

Shelf life       

2 years when properly stored

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